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Primary Location:


University of Alabama at Birmingham

Bone Marrow Transplant & Cell Therapy Program
619 South 19th Street
P302 West Pavilion
Birmingham, AL 35249-6979
Direct phone: (205) 996-2268
http://www.bonemarrow.uab.edu
 

Secondary Location:


The Children's Hospital of Alabama

Lowder Stem Cell Transplant Unit
1600 7th Avenue South
Birmingham, AL 35233
Direct phone: (205) 939-6721
http://sc.chsys.org

Program Description:

  The "single-staff model" UAB BMT Program provides all inpatient and outpatient care on a 24 hour, 7 day schedule in specially designed units at University and Children's Hospitals for adults and children receiving the entire range of blood and marrow transplants.

Contact Information:

  If you have transplant-related questions, please contact Diana Tate, transplant center coordinator, at (205) 934-1911 or by e-mail at dftate@uabmc.edu.

Program Type:

  Adult (ages 14 to 75) and Pediatric (ages 1 to 19)

Attending Physicians:

(Medical Doctors)
 

Adult -

Khaleel Ashraf, Richard Lopez, Donna Salzman, William Vaughan

Pediatric -

David Crawford, Sandhya Kharbanda, Jane Sande

Transplants Performed:

  Marrow/PBSC, single cord, and double cord

Cord blood transplants performed on:

  Pediatric only

Mismatches allowed:

For marrow, PBSC, or cord blood transplant with an unrelated donor. Match criteria may vary based on patient's age, disease type and stage.
 
Marrow/PBSC Cord Blood
Number: One One
Location: case by case basis Amm, CWmm or DQmm with or without T-cell recognition A or B antigen and DRB1 allele or antigen
helpExplain Transplant Center HLA Match Requirements

Estimated Search & Transplant Costs

Costs vary greatly from center to center, and depend on factors such as health insurance, disease type, and disease stage of the patient, as well as center-specific billing policies.
Activation of formal search:$2,397
DR testing of A/B tested donors (per donor):$1,168
Confirmatory typing blood sample (per sample):$1,231
IDM sample collection/testing (per donor):$1,159
High resolution - HLA typing:$2,408
Marrow or PBSC procurement:$47,498
Cord blood procurement (including shipping fees):$49,314

The costs listed above are only a small part of the total cost of a transplant. Contact your transplant center to learn more about costs of actual transplant and follow-up treatment.

helpExplain Transplant Costs at Different Centers

Financial Services:

Financial services at this center could include:

  • Health insurance information
  • Financial assistance
  • Patient-related resources

Resources for financial information

If you have questions about costs and financial services at this transplant center, you can contact the center's financial representative, Syzmanski Fields at (205) 975-5713 or by e-mail at sfields@uabmc.edu.

Many organizations exist to help patients with lodging, transportation and other transplant-related expenses. Visit the National Marrow Donor Program's Patient Organizations database for more information. Financial assistance resources are also listed on this Web site.

Transplant Experience

This center has been performing allogeneic transplants since 1992 and has been an NMDP transplant center since November 1995.

Center-Specific Analysis

This analysis is based on transplants performed from Jan. 1, 2002 through Dec 31, 2006, using unrelated NMDP donors. It only includes patients who were confirmed to be either alive or deceased within one year of transplant.
  1. This center reported survival status data for 67 patients.
  2. The overall disease condition of patients treated at this center was in the low category (1 on a scale of 1 to 5).
  3. The actual one-year survival of these patients was 56.4%.
  4. The predicted one-year survival was 61.9% (with 95% statistical confidence that the predicted survival was between 51.1% and 72.8%).
  5. This center's actual results are similar to the predicted range for this center. National one-year estimated actual survival was 54.0% in the 8,847 patients transplanted in the United States.

For help with understanding these statistics, please see How to Understand NMDP Transplant Center Statistics.

Transplants Performed

(From Jan. 2002 - Dec. 2006)

Marrow

PBSC

Cord
Blood

Auto-
logous

Total

(by transplant type)

Total Non-
Myeloblative transplants*

Unrelated Donor - Adult 28 22 0 --- 50 0
Unrelated Donor - Pediatric 21 10 15 --- 46 2
Related Donor - Adult 15 70 0 --- 85 0
Related Donor - Pediatric 29 6 0 --- 35 0
Autologous (PBSC and Marrow) - Adult --- --- --- 255 255 ---
Autologous (PBSC and Marrow) - Pediatric --- --- --- 52 52 ---
Total (by cell source) 93 108 15 307 523 2

This center performed a total of 106 transplants, all types, in the most recent year (from June 2007 to May 2008)

*The total Non-Myeloblative transplants column shows a subset of the total number of transplants by type.

To locate centers that perform cord blood transplants, use the search tool on this site.

The NMDP also has Transplants by Disease Charts available showing the number of NMDP coordinated transplants by disease category at each U.S. transplant center.

helpExplain Transplant Experience

Survival by Patient's Age, Disease Type and Stage


This data is only based on unrelated transplants performed from Jan. 2002 to Dec. 2006. It also includes one year post-transplant follow-up, through Dec. 2007. The first number represents the number of patients alive at one year post transplant. The second number is a total number of transplanted patients in the particular group.

Key:
CP = chronic phase (1st or 2nd) BP = blastic phase
AP = accelerated phase CR = complete remission (1st, 2nd, 3rd or more)
RLPS = relapse PIF = primary induction failure

Diagnoses

0-10
Yrs

11-17
Yrs

18-30
Yrs

31-40
Yrs

41-50
Yrs

51-60
Yrs

> 60
Yrs

Overall

Acute Lymphoblastic Leukemia 1CR -- -- -- -- 0/1 -- -- 0/1
Acute Lymphoblastic Leukemia 2CR 2/2 1/2 2/2 -- -- -- -- 5/6
Acute Lymphoblastic Leukemia PIF -- -- -- 0/1 -- -- -- 0/1
Acute Myelogenous Leukemia 1CR 0/1 -- 0/1 2/3 1/1 -- -- 3/6
Acute Myelogenous Leukemia 2CR 2/2 -- 0/2 -- 0/2 1/1 -- 3/7
Acute Myelogenous Leukemia 3+CR/RLPS -- 1/1 -- -- -- -- -- 1/1
Acute Myelogenous Leukemia PIF 0/1 -- -- -- -- -- -- 0/1
Chronic Lymphocytic Leukemia -- -- -- -- 1/2 -- -- 1/2
Chronic Myelogenous Leukemia 1CP -- 2/2 1/1 1/2 -- -- -- 4/5
Chronic Myelogenous Leukemia 2CP -- -- 0/1 0/1 1/1 -- -- 1/3
Chronic Myelogenous Leukemia AP -- -- -- -- -- 0/1 -- 0/1
Chronic Myelogenous Leukemia BP -- 0/1 -- -- -- -- -- 0/1
Combined Immunodeficiency 1/1 -- -- -- -- -- -- 1/1
Familial Erythrophagocytic Lymphohistiocytosis 0/1 -- -- -- -- -- -- 0/1
Fanconi Anemia 1/1 -- -- -- -- -- -- 1/1
Hodgkin's Disease -- -- -- -- 1/1 -- -- 1/1
MDS-Chronic Myelomonocytic Leukemia (CMML) -- -- -- -- -- 0/1 -- 0/1
MDS-Other Myelodysplastic Disorder -- -- -- 0/1 0/1 -- -- 0/2
MDS-Refractory Anemia-Excess Blasts -- -- 1/1 -- -- 1/1 -- 2/2
MDS-Refractory Anemia-Excess Blasts in Transformation -- 1/1 -- -- -- -- -- 1/1
MDS-Unknown Myelodysplastic Disorder -- -- -- 1/2 -- -- -- 1/2
Multiple Myeloma -- -- -- 0/1 -- -- -- 0/1
Myelofibro Myeloid Metaplasia -- -- -- 0/1 1/1 -- -- 1/2
Non-Hodgkin's Lymphoma -- -- -- 0/1 0/3 -- -- 0/4
Osteopetrosis 0/1 -- -- -- -- -- -- 0/1
Other Acute Leukemia 1/1 -- -- -- 1/1 -- -- 2/2
Other Immune System Disorder 1/1 -- -- -- -- -- -- 1/1
SCID - Absence of T, Normal B 3/3 -- -- -- -- -- -- 3/3
SCID - Other 2/2 -- -- -- -- -- -- 2/2
Severe Aplastic Anemia -- -- 1/1 2/2 -- -- -- 3/3
Wiskott-Aldrich Syndrome 1/1 -- -- -- -- -- -- 1/1
Total 14/18 5/7 5/9 6/15 6/14 2/4 -- 38/67

helpExplain Survival by Patient Diagnosis and Age


Additional Information
Further information about this center, including the number and type of transplants performed in each of the last three years, and the support groups offered, may be found in the BMT InfoNet Transplant Center Directory: http://www.bmtinfonet.org/centers.

BMT InfoNet (Blood & Marrow Transplant Information Network) is a nonprofit organization that provides information and emotional support to transplant patients and their families.