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UCSF Medical Center

Bone Marrow Transplant Program
505 Parnassus Avenue
San Francisco, CA 94143
Direct phone: (415) 476-2188/353-2051
http://www.ucsfhealth.org

Program Description:

  Our adult program utilizes myeloablative and non-myeloablative approaches for patients with leukemias, myelodysplasis, lymphoma, myeloma and selected solid tumors. Our pediatric program treats children with a variety of cancers, brain tumors, neuroblastoma, genetic diseases and immunodeficiency disorders.

Contact Information:

  If you have transplant-related questions, please contact Helen Crouch, transplant center coordinator, at (415) 353-1506 or by e-mail at helen.crouch@ucsfmedctr.org.

Program Type:

  Adult (ages 18 to 75) and Pediatric (ages 0 to 21)

Attending Physicians:

(Medical Doctors)
 

Adult -

Weiyun Ai, Charalambos Andreadis, Lloyd Damon, Karin Gaensler, Kristin Hege, Lawrence Kaplan, Charles Linker, Thomas Martin, Peter Sayre, Jeffrey Wolf

Pediatric -

Morton Cowan, Christopher Dvorak, Robert Goldsby, Biljana Horn, James Huang

Transplants Performed:

  Marrow/PBSC, single cord, and double cord

Cord blood transplants performed on:

  Adult and pediatric

Mismatches allowed:

For marrow, PBSC, or cord blood transplant with an unrelated donor. Match criteria may vary based on patient's age, disease type and stage.
 
Marrow/PBSC Cord Blood
Number: One Two
Location: Adults: Any locus; Pediatrics: A, B, C, DQB1 A or B antigen and DRB1 allele or antigen
helpExplain Transplant Center HLA Match Requirements

Estimated Search & Transplant Costs

Costs vary greatly from center to center, and depend on factors such as health insurance, disease type, and disease stage of the patient, as well as center-specific billing policies.
Activation of formal search$1,920 - 3,012
DR testing of A/B tested donors (per donor)$693 - 1,668
Confirmatory typing blood sample (per sample)$876 - 5,352
IDM sample collection/testing (per donor)$540 - 2,460
High resolution - HLA typing$330 - 5,280
Marrow or PBSC procurement$58,248 - 99,840
Cord blood procurement (including shipping fees)$29,556 - 101,196
Cord blood typing$2,436 - 8,016

The costs listed above are only a small part of the total cost of a transplant. Contact your transplant center to learn more about costs of actual transplant and follow-up treatment.

helpExplain Transplant Costs at Different Centers

Financial Services:

Financial services at this center could include:

  • Health insurance information
  • Financial assistance
  • Patient-related resources

Resources for financial information

If you have questions about costs and financial services at this transplant center, you can contact the center's financial representative, Shahed Mofidi at (415) 353-1902 or by e-mail at shahed.mofidi@ucsfmedctr.org.

Many organizations exist to help patients with lodging, transportation and other transplant-related expenses. Visit the National Marrow Donor Program's Patient Organizations database for more information. Financial assistance resources are also listed on this Web site.

Transplant Experience

This center has been performing allogeneic transplants since 1982 and has been an NMDP transplant center since March 1991.

Transplants Performed

(Using NMDP and non-NMDP donors from Jan. 2003 to Dec. 2007 as reported by the centers)

Marrow

PBSC

Cord
Blood

Auto-
logous

Total

(by transplant type)

Total Non-
Myeloblative transplants*

Unrelated Donor - Adult 21 82 12 --- 115 64
Unrelated Donor - Pediatric 16 28 14 --- 58 0
Related Donor - Adult 4 104 0 --- 108 48
Related Donor - Pediatric 17 77 2 --- 96 15
Autologous (PBSC and Marrow) - Adult --- --- --- 351 351 ---
Autologous (PBSC and Marrow) - Pediatric --- --- --- 75 75 ---
Total (by cell source) 58 291 28 426 803 127

This center performed a total of 193 transplants, all types, in the most recent year (from June 2008 to May 2009)

*The total Non-Myeloblative transplants column shows a subset of the total number of transplants by type.

To locate centers that perform cord blood transplants, use the search tool on this site.

The NMDP also has Transplants by Disease Charts available showing the number of NMDP coordinated transplants by disease category at each U.S. transplant center.

helpExplain Transplant Experience

Center-Specific Analysis (Using unrelated NMDP donors)

This analysis is based on transplants performed from Jan. 1, 2003 through Dec. 31, 2007, using unrelated NMDP donors. It only includes patients who were confirmed to be either alive or deceased within one year of transplant.
  1. This center reported survival status data for 132 patients.
  2. The overall disease condition of patients treated at this center was in the medium-low risk category (2 on a scale of 1 to 5).
  3. The observed one-year survival of these patients was 67%.
  4. The predicted one-year survival was 60% (with a 95% confidence limit that the predicted survival was between 52% and 68%).
  5. This center's observed results are similar to the predicted range for this center. The estimated national one-year survival was 56.3% in the 9,673 patients transplanted in the United States.

For help with understanding these statistics, please see How to Understand NMDP Transplant Center Statistics.

Survival by Patient's Age, Disease Type and Stage (Using unrelated NMDP donors)


This data is only based on unrelated transplants performed from Jan. 2003 to Dec. 2007. It also includes one year post-transplant follow-up, through Dec. 2008. The first number represents the number of patients alive at one year post transplant. The second number is a total number of transplanted patients in that particular group.

Key:
CP = chronic phase (1st or 2nd) BP = blastic phase
AP = accelerated phase CR = complete remission (1st, 2nd, 3rd or more)
RLPS = relapse PIF = primary induction failure

Diagnoses

0-10
Yrs

11-17
Yrs

18-30
Yrs

31-40
Yrs

41-50
Yrs

51-60
Yrs

> 60
Yrs

Overall

Acute Lymphoblastic Leukemia 1CR 2/2 -- 4/4 2/2 -- 0/1 -- 8/9
Acute Lymphoblastic Leukemia 2CR 1/5 -- 1/3 0/1 -- 0/1 -- 2/10
Acute Lymphoblastic Leukemia 3+CR 2/2 1/1 1/1 -- -- -- -- 4/4
Acute Myelogenous Leukemia 1CR -- 2/2 1/1 -- 0/1 1/3 2/3 6/10
Acute Myelogenous Leukemia 2CR 2/2 -- 1/1 0/1 1/1 2/4 1/1 7/10
Acute Myelogenous Leukemia 3+CR/RLPS -- -- 0/1 -- 1/1 1/4 1/1 3/7
Acute Myelogenous Leukemia PIF -- -- -- -- 1/1 -- 1/2 2/3
Adrenoleukodystrophy 1/2 0/1 -- -- -- -- -- 1/3
Chronic Granulomatous Disease 1/1 -- -- -- -- -- -- 1/1
Chronic Lymphocytic Leukemia -- -- -- -- 1/1 -- 1/1 2/2
Chronic Myelogenous Leukemia 1CP -- -- 1/1 -- 1/1 -- -- 2/2
Chronic Myelogenous Leukemia 2CP -- -- -- -- 1/2 -- -- 1/2
Chronic Myelogenous Leukemia AP -- -- -- -- -- 1/2 -- 1/2
Familial Erythrophagocytic Lymphohistiocytosis 0/1 -- -- -- -- -- -- 0/1
Fanconi Anemia -- 0/2 -- -- -- -- -- 0/2
Hodgkin's Disease -- -- 1/1 2/2 -- -- -- 3/3
Hurler Syndrome 1/1 -- -- -- -- -- -- 1/1
MDS-Chronic Myelomonocytic Leukemia (CMML) -- -- -- 0/1 -- -- 0/1 0/2
MDS-Other Myelodysplastic Disorder -- -- -- -- 1/1 1/1 -- 2/2
MDS-Refractory Anemia 1/1 2/2 1/1 1/1 -- -- -- 5/5
MDS-Refractory Anemia with Ringed Sideroblasts (RARS) -- -- -- -- -- -- 1/1 1/1
MDS-Refractory Anemia-Excess Blasts -- -- -- -- -- -- 0/3 0/3
MDS-Refractory Anemia-Excess Blasts in Transformation -- -- -- -- -- -- 1/1 1/1
Multiple Myeloma -- -- -- -- -- 4/6 0/1 4/7
Non-Hodgkin's Lymphoma -- -- 2/2 2/2 5/7 5/7 0/2 14/20
Other Abnormality of Platelets 1/1 -- -- -- -- -- -- 1/1
Other Acute Leukemia 4/4 -- -- -- -- -- -- 4/4
Other Myelofibrosis -- -- -- -- -- -- 1/1 1/1
Other Non-Malignant Disease 0/1 -- -- -- -- -- -- 0/1
Other Plasma Cell Disorder -- -- -- 1/1 -- -- -- 1/1
Polycythemia Vera -- -- -- -- -- -- 1/1 1/1
Prolymphocytic Leukemia -- -- -- -- -- 1/1 -- 1/1
Severe Aplastic Anemia 1/1 1/1 2/2 1/1 1/1 1/1 -- 7/7
Wiskott-Aldrich Syndrome 1/1 -- -- -- -- -- -- 1/1
X-Linked Lymphoproliferative 1/1 -- -- -- -- -- -- 1/1
Total 19/26 6/9 15/18 9/12 13/17 17/31 10/19 89/132

helpExplain Survival by Patient Diagnosis and Age


Additional Information
Further information about this center, including the number and type of transplants performed in each of the last three years, and the support groups offered, may be found in the BMT InfoNet Transplant Center Directory: http://www.bmtinfonet.org/transplantcenters.

BMT InfoNet (Blood & Marrow Transplant Information Network) is a nonprofit organization that provides information and emotional support to transplant patients and their families.