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City of Hope National Medical Center

Hematology & Hematopoietic Cell Transplant
1500 East Duarte Road
Duarte, CA 91010-0269
Direct phone: (626) 256-4673
Toll-free phone: (800) 535-7119
http://www.coh.org

Program Description:

  City of Hope is an NCI-designated Comprehensive Cancer Center. Areas of research include DNA typing for donor selection, new agents for prevention and treatment of GVHD, use of peripheral stem cells, reduced intensity or low-dose regimens for older patients or those with co-morbid medical conditions.

Contact Information:

  If you have transplant-related questions, please contact Jean Parisi, transplant center coordinator, at (800) 535-7119 (ext. 64157) or by e-mail at jblaylock@coh.org.

Program Type:

  Adult (ages 18 to 70) and Pediatric (ages 0 to 18)

Attending Physicians:

(Medical Doctors)
 

Adult -

Ravi Bhatia, Ji-Lian Cai, Maria Delioukina, Len Farol, Stephen Forman, Chatchada Karanes, Mark Kirschbaum, Neil Kogut, Amrita Krishnan, Auayporn Nademanee, Ryokato Nakamura, Margaret O'Donnell, Pablo Parker, Leslie Popplewell, Vinod Pullarkat, Faroozhi Sahebi, Eileen Smith, David Snyder, Ricardo Spielberger, Anthony Stein

Pediatric -

Ellen Bolotin, Len Farol, Anna Pawlowska, Joseph Rosenthal

Transplants Performed:

  Marrow/PBSC, single cord, and double cord

Cord blood transplants performed on:

  Adult and pediatric

Mismatches allowed:

For marrow, PBSC, or cord blood transplant with an unrelated donor. Match criteria may vary based on patient's age, disease type and stage.
 
Marrow/PBSC Cord Blood
Number: Two Two
Location: Any locus A or B antigen and DRB1 allele or antigen
helpExplain Transplant Center HLA Match Requirements

Estimated Search & Transplant Costs

Costs vary greatly from center to center, and depend on factors such as health insurance, disease type, and disease stage of the patient, as well as center-specific billing policies.
Activation of formal search:$975 - 2,535
DR testing of A/B tested donors (per donor):$429 - 1,261
Confirmatory typing blood sample (per sample):$44 - 2,769
IDM sample collection/testing (per donor):$280 - 1,274
High resolution - HLA typing:$280 - 1,755
Marrow or PBSC procurement:$18,818 - 51,805
Cord blood procurement (including shipping fees):$15,698 - 53,632

The costs listed above are only a small part of the total cost of a transplant. Contact your transplant center to learn more about costs of actual transplant and follow-up treatment.

helpExplain Transplant Costs at Different Centers

Financial Services:

Financial services at this center could include:

  • Health insurance information
  • Financial assistance
  • Patient-related resources

Resources for financial information

If you have questions about costs and financial services at this transplant center, you can contact the center's financial representative, June Richetts at (800) 535-7119 (ext. 68806) or by e-mail at jrichetts@coh.org.

Many organizations exist to help patients with lodging, transportation and other transplant-related expenses. Visit the National Marrow Donor Program's Patient Organizations database for more information. Financial assistance resources are also listed on this Web site.

Transplant Experience

This center has been performing allogeneic transplants since 1975 and has been an NMDP transplant center since September 1989.

Center-Specific Analysis

This analysis is based on transplants performed from Jan. 1, 2002 through Dec 31, 2006, using unrelated NMDP donors. It only includes patients who were confirmed to be either alive or deceased within one year of transplant.
  1. This center reported survival status data for 330 patients.
  2. The overall disease condition of patients treated at this center was in the medium-high category (4 on a scale of 1 to 5).
  3. The actual one-year survival of these patients was 60.3%.
  4. The predicted one-year survival was 50.5% (with 95% statistical confidence that the predicted survival was between 45.6% and 55.8%).
  5. This center's actual results are above the predicted range for this center. National one-year estimated actual survival was 54.0% in the 8,847 patients transplanted in the United States.

For help with understanding these statistics, please see How to Understand NMDP Transplant Center Statistics.

Transplants Performed

(From Jan. 2002 - Dec. 2006)

Marrow

PBSC

Cord
Blood

Auto-
logous

Total

(by transplant type)

Total Non-
Myeloblative transplants*

Unrelated Donor - Adult 68 274 13 --- 355 189
Unrelated Donor - Pediatric 21 30 30 --- 81 19
Related Donor - Adult 27 449 0 --- 476 236
Related Donor - Pediatric 31 42 5 --- 78 11
Autologous (PBSC and Marrow) - Adult --- --- --- 1241 1241 ---
Autologous (PBSC and Marrow) - Pediatric --- --- --- 38 38 ---
Total (by cell source) 147 795 48 1279 2269 455

This center performed a total of 494 transplants, all types, in the most recent year (from June 2007 to May 2008)

*The total Non-Myeloblative transplants column shows a subset of the total number of transplants by type.

To locate centers that perform cord blood transplants, use the search tool on this site.

The NMDP also has Transplants by Disease Charts available showing the number of NMDP coordinated transplants by disease category at each U.S. transplant center.

helpExplain Transplant Experience

Survival by Patient's Age, Disease Type and Stage


This data is only based on unrelated transplants performed from Jan. 2002 to Dec. 2006. It also includes one year post-transplant follow-up, through Dec. 2007. The first number represents the number of patients alive at one year post transplant. The second number is a total number of transplanted patients in the particular group.

Key:
CP = chronic phase (1st or 2nd) BP = blastic phase
AP = accelerated phase CR = complete remission (1st, 2nd, 3rd or more)
RLPS = relapse PIF = primary induction failure

Diagnoses

0-10
Yrs

11-17
Yrs

18-30
Yrs

31-40
Yrs

41-50
Yrs

51-60
Yrs

> 60
Yrs

Overall

Acute Bilineage Leukemia -- -- -- 1/1 1/1 -- 0/1 2/3
Acute Lymphoblastic Leukemia 1CR 1/1 2/3 3/4 6/7 1/1 4/6 2/2 19/24
Acute Lymphoblastic Leukemia 2CR 1/2 3/6 3/5 4/4 1/3 0/1 -- 12/21
Acute Lymphoblastic Leukemia 3+CR -- 0/1 1/2 -- 0/1 -- -- 1/4
Acute Lymphoblastic Leukemia PIF -- 1/1 3/3 -- 0/2 -- 1/1 5/7
Acute Lymphoblastic Leukemia RLPS 0/1 1/1 2/7 1/2 2/3 0/1 -- 6/15
Acute Myelogenous Leukemia 1CR 1/2 2/3 -- 3/4 3/8 10/16 1/4 20/37
Acute Myelogenous Leukemia 2CR 2/3 3/4 2/4 -- 3/4 5/6 1/1 16/22
Acute Myelogenous Leukemia 3+CR/RLPS 1/2 -- 4/5 1/1 1/8 2/7 3/5 12/28
Acute Myelogenous Leukemia PIF -- 1/1 2/3 1/1 3/4 5/9 1/3 13/21
Acute Undifferentiated Leukemia -- -- -- 0/1 -- -- -- 0/1
Chronic Lymphocytic Leukemia -- -- -- 1/1 -- 1/2 1/1 3/4
Chronic Myelogenous Leukemia 1CP -- -- 7/9 2/4 2/3 2/2 -- 13/18
Chronic Myelogenous Leukemia 2CP -- -- 0/1 -- 3/3 1/1 -- 4/5
Chronic Myelogenous Leukemia AP -- -- -- 2/3 3/3 0/1 1/1 6/8
Chronic Myelogenous Leukemia BP -- -- -- 1/1 0/1 -- -- 1/2
Fanconi Anemia 1/2 -- 1/1 -- -- -- -- 2/3
Hodgkin's Disease -- -- 1/2 2/3 1/1 -- -- 4/6
MDS-Chronic Myelomonocytic Leukemia (CMML) -- -- -- -- -- -- 1/1 1/1
MDS-Other Myelodysplastic Disorder -- 1/1 -- 0/1 2/2 0/1 0/1 3/6
MDS-Refractory Anemia -- -- -- 1/1 3/4 0/1 -- 4/6
MDS-Refractory Anemia with Ringed Sideroblasts (RARS) -- -- -- -- -- 0/1 -- 0/1
MDS-Refractory Anemia-Excess Blasts -- 0/1 -- 1/1 2/3 3/4 0/1 6/10
MDS-Refractory Anemia-Excess Blasts in Transformation -- -- -- 1/1 0/1 -- -- 1/2
MDS-Unknown Myelodysplastic Disorder -- -- 1/1 -- 1/1 -- -- 2/2
Multiple Myeloma -- -- 0/1 -- 0/1 1/1 -- 1/3
Myelofibro Myeloid Metaplasia -- 0/1 -- -- 1/2 4/6 3/3 8/12
Non-Hodgkin's Lymphoma 0/2 -- 5/8 3/9 9/10 8/11 -- 25/40
Osteopetrosis 0/1 -- -- -- -- -- -- 0/1
Other Myelofibrosis -- -- -- -- 1/1 1/1 -- 2/2
Other Non-Malignant Disease -- -- -- 0/1 -- -- -- 0/1
Paroxysmal Nocturnal Hemoglobinuria -- -- 1/1 -- -- -- -- 1/1
Plasma Cell Leukemia -- -- -- -- -- 0/1 -- 0/1
Pure Red Cell Aplasia -- -- -- 1/1 -- -- -- 1/1
Renal Cell Carcinoma -- -- -- -- -- 1/1 -- 1/1
Severe Aplastic Anemia 0/1 2/2 2/4 1/2 -- 1/1 -- 6/10
Total 7/17 16/25 38/61 33/50 43/71 49/81 15/25 201/330

helpExplain Survival by Patient Diagnosis and Age


Additional Information
Further information about this center, including the number and type of transplants performed in each of the last three years, and the support groups offered, may be found in the BMT InfoNet Transplant Center Directory: http://www.bmtinfonet.org/centers.

BMT InfoNet (Blood & Marrow Transplant Information Network) is a nonprofit organization that provides information and emotional support to transplant patients and their families.