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Children's National Medical Center

Center for Cancer and Blood Disorders
111 Michigan Avenue, Northwest
Washington, DC 20010-2970
Direct phone: (202) 476-2800
http://www.dcchildrens.com

Program Description:

  The stem cell transplant program at CNMC has performed over 350 pediatric transplants. The current focus of our program is on alternative donor transplants (cord blood, bone marrow and PBSC) and the evaluation of non-myeloablative approaches to the treatment of non-malignant pediatric diseases.

Contact Information:

  If you have transplant-related questions, please contact Kay Ayers, transplant center coordinator, at (202) 476-5763 or by e-mail at kayers@cnmc.org.

Program Type:

  Pediatric (ages 0 to 21)

Attending Physicians:

(Medical Doctors)
 

Pediatric -

Terry Fry, Naynesh Kamani, Aviva Krauss, Brett Loechelt, Evelio Perez-Albuerne

Transplants Performed:

  Marrow/PBSC, single cord, and double cord

Cord blood transplants performed on:

  Pediatric only

Mismatches allowed:

For marrow, PBSC, or cord blood transplant with an unrelated donor. Match criteria may vary based on patient's age, disease type and stage.
 
Marrow/PBSC Cord Blood
Number: One Two
Location: A, B, C, DQB1 A or B antigen only
helpExplain Transplant Center HLA Match Requirements

Estimated Search & Transplant Costs

Costs vary greatly from center to center, and depend on factors such as health insurance, disease type, and disease stage of the patient, as well as center-specific billing policies.
Activation of formal search:$750 - 1,950
DR testing of A/B tested donors (per donor):$440 - 880
Confirmatory typing blood sample (per sample):$440 - 1,370
IDM sample collection/testing (per donor):$215 - 980
High resolution - HLA typing:$440 - 880
Marrow or PBSC procurement:$15,200 - 41,843
Cord blood procurement (including shipping fees):$12,679 - 43,318

The costs listed above are only a small part of the total cost of a transplant. Contact your transplant center to learn more about costs of actual transplant and follow-up treatment.

helpExplain Transplant Costs at Different Centers

Financial Services:

Financial services at this center could include:

  • Health insurance information
  • Financial assistance
  • Patient-related resources

Resources for financial information

If you have questions about costs and financial services at this transplant center, you can contact the center's financial representative, Judith Sealey at (202) 476-2745 or by e-mail at jsealey@cnmc.org.

Many organizations exist to help patients with lodging, transportation and other transplant-related expenses. Visit the National Marrow Donor Program's Patient Organizations database for more information. Financial assistance resources are also listed on this Web site.

Transplant Experience

This center has been performing allogeneic transplants since 1988 and has been an NMDP transplant center since September 1992.

Center-Specific Analysis

This analysis is based on transplants performed from Jan. 1, 2002 through Dec 31, 2006, using unrelated NMDP donors. It only includes patients who were confirmed to be either alive or deceased within one year of transplant.
  1. This center reported survival status data for 26 patients.
  2. The overall disease condition of patients treated at this center was in the low category (1 on a scale of 1 to 5).
  3. The actual one-year survival of these patients was 55.1%.
  4. The predicted one-year survival was 60.7% (with 95% statistical confidence that the predicted survival was between 42.8% and 78.8%).
  5. This center's actual results are similar to the predicted range for this center. National one-year estimated actual survival was 54.0% in the 8,847 patients transplanted in the United States.

For help with understanding these statistics, please see How to Understand NMDP Transplant Center Statistics.

Transplants Performed

(From Jan. 2002 - Dec. 2006)

Marrow

PBSC

Cord
Blood

Auto-
logous

Total

(by transplant type)

Total Non-
Myeloblative transplants*

Unrelated Donor - Adult 0 0 0 --- 0 0
Unrelated Donor - Pediatric 18 6 14 --- 38 0
Related Donor - Adult 0 0 0 --- 0 0
Related Donor - Pediatric 26 5 0 --- 31 4
Autologous (PBSC and Marrow) - Adult --- --- --- 0 0 ---
Autologous (PBSC and Marrow) - Pediatric --- --- --- 71 71 ---
Total (by cell source) 44 11 14 71 140 4

This center performed a total of 29 transplants, all types, in the most recent year (from June 2007 to May 2008)

*The total Non-Myeloblative transplants column shows a subset of the total number of transplants by type.

To locate centers that perform cord blood transplants, use the search tool on this site.

The NMDP also has Transplants by Disease Charts available showing the number of NMDP coordinated transplants by disease category at each U.S. transplant center.

helpExplain Transplant Experience

Survival by Patient's Age, Disease Type and Stage


This data is only based on unrelated transplants performed from Jan. 2002 to Dec. 2006. It also includes one year post-transplant follow-up, through Dec. 2007. The first number represents the number of patients alive at one year post transplant. The second number is a total number of transplanted patients in the particular group.

Key:
CP = chronic phase (1st or 2nd) BP = blastic phase
AP = accelerated phase CR = complete remission (1st, 2nd, 3rd or more)
RLPS = relapse PIF = primary induction failure

Diagnoses

0-10
Yrs

11-17
Yrs

18-30
Yrs

31-40
Yrs

41-50
Yrs

51-60
Yrs

> 60
Yrs

Overall

Acute Lymphoblastic Leukemia 1CR 1/1 1/1 0/1 -- -- -- -- 2/3
Acute Lymphoblastic Leukemia 2CR 4/5 0/1 -- -- -- -- -- 4/6
Acute Lymphoblastic Leukemia 3+CR -- 0/1 -- -- -- -- -- 0/1
Acute Lymphoblastic Leukemia RLPS 0/1 -- -- -- -- -- -- 0/1
Acute Myelogenous Leukemia 2CR 1/1 2/2 -- -- -- -- -- 3/3
Acute Myelogenous Leukemia 3+CR/RLPS 1/1 0/1 -- -- -- -- -- 1/2
Acute Myelogenous Leukemia PIF 1/1 -- -- -- -- -- -- 1/1
Beta Thalassemia Major -- -- 0/1 -- -- -- -- 0/1
Chronic Myelogenous Leukemia BP -- 0/1 -- -- -- -- -- 0/1
Combined Immunodeficiency 1/1 -- -- -- -- -- -- 1/1
Familial Erythrophagocytic Lymphohistiocytosis 2/2 -- -- -- -- -- -- 2/2
Hemophagocytosis 0/1 -- -- -- -- -- -- 0/1
SCID - Absence of T, Normal B 1/1 -- -- -- -- -- -- 1/1
Severe Aplastic Anemia 0/1 -- -- -- -- -- -- 0/1
Sickle Cell Anemia -- 0/1 -- -- -- -- -- 0/1
Total 12/16 3/8 0/2 -- -- -- -- 15/26

helpExplain Survival by Patient Diagnosis and Age


Additional Information
Further information about this center, including the number and type of transplants performed in each of the last three years, and the support groups offered, may be found in the BMT InfoNet Transplant Center Directory: http://www.bmtinfonet.org/centers.

BMT InfoNet (Blood & Marrow Transplant Information Network) is a nonprofit organization that provides information and emotional support to transplant patients and their families.