FeedsSaving Lives through Blood and Marrow Transplantation: 20 Years of the NMDP
The National Marrow Donor Program® (NMDP) is celebrating 20 years of extraordinary accomplishments in helping patients who need an unrelated blood, marrow, or cord blood transplant.
Read about the significant research and resources that have now helped more than 30,000 patients (more than 4,300 this year alone). The NMDP worked with leaders in the field of blood and marrow transplantation to publish a supplement to the medical journal Biology of Blood and Marrow Transplantation (BBMT).
The seven chapters of the supplement describe the collaborative contributions of the NMDP and its Network in advancing blood and marrow transplant science to save more lives and provide insight into the future directions of transplantation.
To access the entire BBMT supplement content, use the links below:
- Order a printed copy of the BBMT supplement
- View the entire supplement online
- View by individual chapters using links below
You may also view a PowerPoint® file with 13 survival curves from the BBMT supplement showing significant improvements in NMDP transplant outcomes over time.
View highlights with links to each chapter:
Introduction
http://www.bbmt.org/article/S1083-8791(08)00247-4/fulltext
- Supplement editor Dr. Daniel Weisdorf writes of the 20-year history of the NMDP
Chapter 1. 20-years of the NMDP: innovation and growth http://www.bbmt.org/article/S1083-8791(08)00230-9/fulltext
- The dramatic growth of NMDP's diverse Be The Match Registry SM, now over 7 million donors, helps more patients in need
- Trends in blood and marrow transplantation such as conditioning regimens and changing patient demographics
- Advances and trends in three cell sources: marrow, cord blood, and peripheral blood stem cells (PBSC)
- Reasons for significant advances in the ability to successfully transplant patients older than 55 years
- The NMDP's contributions to donor and patient safety and advocacy, access to transplant, and research
Chapter 2. Improving transplant survival in adults http://www.bbmt.org/article/S1083-8791(08)00249-8/fulltext
- Research demonstrating continuous improvement in survival, while treating older patients (median age 46.7 yrs.)
- Survival for severe aplastic anemia has doubled in just 10 years
Chapter 3. Improving transplant survival in pediatric acute leukemia
http://www.bbmt.org/article/S1083-8791(08)00228-0/fulltext
- A dramatic decline in transplant-related complications has led to improved survival
- Survival rates for children transplanted in first complete remission, now greater than 70% at two years
- Trends in using cord blood for children with high-risk disease and who need to move quickly to transplant
Chapter 4. Safe collection and transportation of cellular products
http://www.bbmt.org/article/S1083-8791(08)00244-9/fulltext
- A thorough review of donor collection activities, product integrity and transportation
- Comprehensive statistics on the use and incidence of multiple donations
Chapter 5. Monitoring marrow and PBSC donor safety and recovery
http://www.bbmt.org/article/S1083-8791(08)00229-2/fulltext
- A review of the similarities and differences in the recovery profiles of PBSC and marrow donors
Chapter 6. Using research to streamline donor search
http://www.bbmt.org/article/S1083-8791(08)00183-3/fulltext
- The NMDP's leadership in DNA-based HLA typing to improve matching, and ultimately, survival
- HapLogicSM - the NMDP's state-of-the-art matching algorithm - helps patients proceed to transplant faster
Chapter 7. Optimal donor and patient matching guidelines
http://www.bbmt.org/article/S1083-8791(08)00274-7/fulltext
- The latest HLA research supporting newly updated NMDP guidelines on donor-recipient matching
- The importance of non-HLA factors when selecting donors
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Weisdorf D, (Ed.). The National Marrow Donor Program reports to the community on 20 years of unrelated donor hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2008; 14(9, Suppl. 3):1-60.
